Studies in formulation and pharmacotechnical evaluation of controlled release transdermal delivery system of bupropion

The objective of the present study was to design and evaluate unilaminate transdermal adhesive matrix systems capable of diffusing bupropion base at a constant rate over an extended period of time as an alternative route of administration. Unilaminate transdermal adhesive matrices have been fabricat...

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Veröffentlicht in:	AAPS PharmSciTech 2003, Vol.4 (1), p.E3-26
Hauptverfasser:	Gondaliya, Deepak, Pundarikakshudu, Kilambi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesives - chemistry Antidepressive Agents, Second-Generation - administration & dosage Antidepressive Agents, Second-Generation - metabolism Bupropion - administration & dosage Bupropion - metabolism Delayed-Action Preparations Diffusion Drug Compounding Epidermis - metabolism Humans Kinetics Plasticizers - chemistry Polymethacrylic Acids - chemistry
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