Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase β1 -subunit
Abstract Na,K-ATPase is composed of two essential α- and β-subunits, both of which have multiple isoforms. Evidence indicates that the Na,K-ATPase enzymatic activity as well as its α1 , α3 and β1 isoforms are reduced in the failing human heart. The catalytic α-subunit is the receptor for cardiac gly...
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Veröffentlicht in: | Journal of molecular and cellular cardiology 2009-10, Vol.47 (4), p.552-560 |
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Hauptverfasser: | , , , , , , , , , , , , |
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Sprache: | eng |
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