Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase β1 -subunit

Abstract Na,K-ATPase is composed of two essential α- and β-subunits, both of which have multiple isoforms. Evidence indicates that the Na,K-ATPase enzymatic activity as well as its α1 , α3 and β1 isoforms are reduced in the failing human heart. The catalytic α-subunit is the receptor for cardiac gly...

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Veröffentlicht in:Journal of molecular and cellular cardiology 2009-10, Vol.47 (4), p.552-560
Hauptverfasser: Barwe, Sonali P, Jordan, Maria C, Skay, Anna, Inge, Landon, Rajasekaran, Sigrid A, Wolle, Daniel, Johnson, Christina L, Neco, Patricia, Fang, Kun, Rozengurt, Nora, Goldhaber, Joshua I, Roos, Kenneth P, Rajasekaran, Ayyappan K
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Sprache:eng
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