Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells

The FOXO1 transcription factor orchestrates the regulation of genes involved in the apoptotic response, cell cycle checkpoints, and cellular metabolism. FOXO1 is a putative tumor suppressor, and the expression of this gene is dysregulated in some cancers, including prostate and endometrial cancers....

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Veröffentlicht in:	The Journal of biological chemistry 2009-08, Vol.284 (35), p.23204-23216
Hauptverfasser:	Guttilla, Irene K., White, Bruce A.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Breast Neoplasms - genetics Breast Neoplasms - metabolism Cell Line, Tumor Down-Regulation Forkhead Box Protein O1 Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Gene Expression Regulation Humans MicroRNAs - genetics MicroRNAs - metabolism RNA-Mediated Regulation and Noncoding RNAs
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