CRTC2 (TORC2) Contributes to the Transcriptional Response to Fasting in the Liver but Is Not Required for the Maintenance of Glucose Homeostasis

The liver contributes to glucose homeostasis by promoting either storage or production of glucose, depending on the physiological state. The cAMP response element-binding protein (CREB) is a principal regulator of genes involved in coordinating the hepatic response to fasting, but its mechanism of g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell metabolism 2009-07, Vol.10 (1), p.55-62
Hauptverfasser:	Le Lay, John, Tuteja, Geetu, White, Peter, Dhir, Ravindra, Ahima, Rexford, Kaestner, Klaus H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Fasting Glucagon - metabolism Glucose - metabolism Glucose-6-Phosphatase - metabolism HUMDISEASE Liver - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Protein-Serine-Threonine Kinases - metabolism Trans-Activators - deficiency Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors Transcription, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!