Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin

Recent advances in crystallizing integral membrane proteins have led to atomic models for the structures of several seven-helix membrane proteins, including those in the G-protein-coupled receptor family. Further steps toward exploring structure–function relationships will undoubtedly involve determ...

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Veröffentlicht in:Current opinion in structural biology 2009-08, Vol.19 (4), p.433-439
Hauptverfasser: Hirai, Teruhisa, Subramaniam, Sriram, Lanyi, Janos K
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Sprache:eng
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