Low plasma selenium concentrations and mortality among older community-dwelling adults: the InCHIANTI Study

Low plasma selenium concentrations and mortality among older community-dwelling adults: the InCHIANTI Study

Aims : We examined the relationship between plasma selenium levels at enrollment and all-cause mortality over a 6-year period among participants in the InCHIANTI study. Methods : 1042 men and women ≥65 years from the InCHIANTI study, a population-based study of older adults living in the Chianti reg...

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Veröffentlicht in:Aging clinical and experimental research 2008-04, Vol.20 (2), p.153-158
Hauptverfasser: Lauretani, Fulvio, Semba, Richard D., Bandinelli, Stefania, Ray, Amanda L., Ruggiero, Carmelinda, Cherubini, Antonio, Guralnik, Jack M., Ferrucci, Luigi
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Cohort Studies
Data Collection
Female
Follow-Up Studies
Geriatrics/Gerontology
Health risk assessment
Humans
Italy - epidemiology
Kaplan-Meier Estimate
Male
Medicine
Medicine & Public Health
Mortality
Older people
Original Article
Risk Factors
Selenium
Selenium - blood
Selenium - deficiency
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Zusammenfassung:Aims : We examined the relationship between plasma selenium levels at enrollment and all-cause mortality over a 6-year period among participants in the InCHIANTI study. Methods : 1042 men and women ≥65 years from the InCHIANTI study, a population-based study of older adults living in the Chianti region of Tuscany, a population-based cohort in Tuscany, Italy. Plasma selenium was measured at enrollment (1998–2000), and vital status was ascertained until May 2006. Results : During follow-up, 237 participants (22.7%) died. At enrollment, mean (SD) plasma selenium concentrations among participants who survived or died were 0.96 (0.14) and 0.87 (0.18) μmol/L (p
ISSN:1594-0667
1720-8319
DOI:10.1007/BF03324762