Endothelin Mediates Some of the Renal Actions of Acutely Administered Angiotensin II

Recent studies suggest that endogenous endothelin mediates much of the vasoconstrictor activity and vascular fibrotic damage caused by chronic administration of angiotensin II. The present study uses the mixed endothelin-A and endothelin-B receptor antagonist bosentan and the endothelin-A-selective...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2001-07, Vol.38 (1), p.105-109
Hauptverfasser:	Riggleman, Amy, Harvey, Jeff, Baylis, Chris
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Animals Antihypertensive agents Biological and medical sciences Blood Pressure - drug effects Blood Pressure - physiology Bosentan Cardiovascular system Endothelin Receptor Antagonists Endothelins - physiology Kidney - drug effects Kidney - metabolism Kidney - physiology Kidney Function Tests Male Medical sciences Peptides, Cyclic - pharmacology Pharmacology. Drug treatments Pressoreceptors - drug effects Pressoreceptors - physiology Rats Rats, Sprague-Dawley Receptor, Endothelin A Receptor, Endothelin B Sulfonamides - pharmacology
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