In Vivo Visualization of Alzheimer’s Amyloid Plaques by MRI in Transgenic Mice Without a Contrast Agent

One of the cardinal pathologic features of Alzheimer’s disease (AD) is formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop “human-like” plaques, providing a mechanism...

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Veröffentlicht in:	Magnetic resonance in medicine 2004-12, Vol.52 (6), p.1263-1271
Hauptverfasser:	Jack, Clifford R., Garwood, Michael, Wengenack, Thomas M., Borowski, Bret, Curran, Geoffrey L., Lin, Joseph, Adriany, Gregor, Grohn, Olli H.J., Grimm, Roger, Poduslo, Joseph F.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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