Merkel Cells Are Essential for Light-Touch Responses

The peripheral nervous system detects different somatosensory stimuli, including pain, temperature, and touch. Merkel cell-neurite complexes are touch receptors composed of sensory afferents and Merkel cells. The role that Merkel cells play in light-touch responses has been the center of controversy...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2009-06, Vol.324 (5934), p.1580-1582
Hauptverfasser:	Maricich, Stephen M, Wellnitz, Scott A, Nelson, Aislyn M, Lesniak, Daine R, Gerling, Gregory J, Lumpkin, Ellen A, Zoghbi, Huda Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Biological and medical sciences Cellular biology Embryos Female Foot Fundamental and applied biological sciences. Psychology Grants Hair Innervation Male Merkel cells Merkel Cells - metabolism Merkel Cells - physiology Mice Mice, Inbred C57BL Mice, Knockout Nerves Nervous system Neurons Salt domes Sense of touch Sensory perception Skin Skin - cytology Skin Physiological Phenomena Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Touch - physiology Vertebrates: nervous system and sense organs
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