Allosteric Site Variants of Haemophilus influenzae β-Carbonic Anhdyrase

Haemophilus influenzae β-carbonic anhydrase (HICA) is hypothesized to be an allosteric protein that is regulated by the binding of bicarbonate ion to a non-catalytic (inhibitory) site that controls the ligation of Asp44 to the catalytically essential zinc ion. We report here the X-ray crystallograph...

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Veröffentlicht in:Biochemistry (Easton) 2009-07, Vol.48 (26), p.6146-6156
Hauptverfasser: Rowlett, Roger S., Tu, Chingkuang, Lee, Joseph, Herman, Ariel G., Chapnick, Douglas A., Shah, Shalini H., Gareiss, Peter C.
Format: Artikel
Sprache:eng
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