Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples

Recessive mutations in the phenylalanine hydroxylase (PAH) gene predispose to phenylketonuria (PKU) in conjunction with dietary exposure to phenylalanine. Previous studies have suggested PAH variations could confer risk for schizophrenia, but comprehensive follow‐up has not been reported. We analyze...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Neuropsychiatric genetics, 2009-06, Vol.150B (4), p.560-569
Hauptverfasser:	Talkowski, Michael E., McClain, Lora, Allen, Trina, Bradford, L. DiAnne, Calkins, Monica, Edwards, Neil, Georgieva, Lyudmila, Go, Rodney, Gur, Ruben, Gur, Raquel, Kirov, George, Chowdari, Kodavali, Kwentus, Joseph, Lyons, Paul, Mansour, Hader, McEvoy, Joseph, O'Donovan, Michael C., O'Jile, Judith, Owen, Michael J., Santos, Alberto, Savage, Robert, Toncheva, Draga, Vockley, Gerard, Wood, Joel, Devlin, Bernie, Nimgaonkar, Vishwajit L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Alleles Biological and medical sciences Case-Control Studies Female Gene Frequency - genetics Genetic Predisposition to Disease Genotype Humans Linkage Disequilibrium - genetics Male Medical genetics Medical sciences Mutation - genetics phenylalanine hydroxylase Phenylalanine Hydroxylase - genetics Phenylketonurias - genetics polymorphism Polymorphism, Single Nucleotide - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!