A Divergent Synthesis of the Δ13-9-Isofurans

A stereodivergent total synthesis of the Δ13-9-isofurans has been developed. The four core substituted tetrahydrofurans were prepared by the Sharpless asymmetric epoxidation and Sharpless asymmetric dihydroxylation followed by cascade cyclization. The relative configuration at C-8 was inverted by ox...

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Veröffentlicht in:	Journal of organic chemistry 2009-08, Vol.74 (15), p.5516-5522
Hauptverfasser:	Taber, Douglass F, Gu, Peiming, Li, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Condensed benzenic and aromatic compounds Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Noncondensed benzenic compounds Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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