CXC chemokines play a critical role in liver injury, recovery, and regeneration

Abstract Background Hepatic ischemia/reperfusion (I/R) injury is a principal consideration of trauma, resectional liver surgery, and transplantation. Despite improvements in supportive care, hepatic I/R injury continues to negatively impact patient outcomes because of significant tissue damage and o...

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Veröffentlicht in:	The American journal of surgery 2009-09, Vol.198 (3), p.415-419
Hauptverfasser:	Clarke, Callisia N., M.D, Kuboki, Satoshi, M.D, Tevar, Amit, M.D, Lentsch, Alex B., Ph.D, Edwards, Michael, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Biological and medical sciences Cardiology. Vascular system Cell cycle Chemokines Chemokines, CXC - metabolism Chemokines, CXC - physiology CXC chemokines Cytokines Endothelium General aspects Hepatocytes Humans Impact damage Inflammation Inflammation Mediators - metabolism Inflammation Mediators - physiology Inflammatory response Injuries Ischemia Ischemia - metabolism Ischemia - physiopathology Ischemia/Reperfusion Liver Liver regeneration Liver Regeneration - physiology Liver transplantation Medical sciences Neutrophils Recovery Recovery of Function - physiology Regeneration Regulators Reperfusion Reperfusion Injury - metabolism Reperfusion Injury - physiopathology Rodents Signal Transduction Surgery Transcription factors Transplantation Trauma Tumor necrosis factor-TNF
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