Brain-Derived Neurotrophic Factor in Infants <32 Weeks Gestational Age: Correlation With Antenatal Factors and Postnatal Outcomes

Neurotrophins (NTs) play important roles in brain growth and development. Cord blood (CB) brain-derived neurotrophic factor (BDNF) concentrations increase with gestational age but data regarding postnatal changes are limited. We measured BDNF concentrations after birth in 33 preterm infants

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Bibliographische Detailangaben
Veröffentlicht in:	Pediatric research 2009-05, Vol.65 (5), p.548-552
Hauptverfasser:	Rao, Rakesh, Mashburn, Charles B, Mao, Jingnan, Wadhwa, Nitin, Smith, George M, Desai, Nirmala S
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Biological and medical sciences Birth Weight Brain - drug effects Brain - growth & development Brain - metabolism Brain-Derived Neurotrophic Factor - blood Bronchopulmonary Dysplasia - blood Cerebral Hemorrhage - blood Child Development clinical-investigation Drug Administration Schedule Enterocolitis, Necrotizing - blood Female Fetal Blood - metabolism Fetal Membranes, Premature Rupture - blood General aspects Gestational Age Humans Infant, Newborn Infant, Premature Male Medical sciences Medicine Medicine & Public Health Multivariate Analysis Pediatric Surgery Pediatrics Pregnancy Prospective Studies Retinopathy of Prematurity - blood Steroids - administration & dosage
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Beschreibung
Zusammenfassung:	Neurotrophins (NTs) play important roles in brain growth and development. Cord blood (CB) brain-derived neurotrophic factor (BDNF) concentrations increase with gestational age but data regarding postnatal changes are limited. We measured BDNF concentrations after birth in 33 preterm infants
ISSN:	0031-3998 1530-0447 1530-0447
DOI:	10.1203/PDR.0b013e31819d9ea5