Regulation of fission yeast myosin-II function and contractile ring dynamics by regulatory light-chain and heavy-chain phosphorylation

We investigated the role of regulatory light-chain (Rlc1p) and heavy-chain phosphorylation in controlling fission yeast myosin-II (Myo2p) motor activity and function during cytokinesis. Phosphorylation of Rlc1p leads to a fourfold increase in Myo2p's in vitro motility rate, which ensures effect...

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Veröffentlicht in:	Molecular biology of the cell 2009-09, Vol.20 (17), p.3941-3952
Hauptverfasser:	Sladewski, Thomas E, Previs, Michael J, Lord, Matthew
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Amino Acid Sequence Cytokinesis - physiology Cytoskeleton - metabolism Molecular Sequence Data Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism Myosin Type II - genetics Myosin Type II - metabolism Phosphorylation Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Schizosaccharomyces - cytology Schizosaccharomyces - physiology Schizosaccharomyces pombe Proteins - genetics Schizosaccharomyces pombe Proteins - metabolism
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