Role of aquaporin-1 in trabecular meshwork cell homeostasis during mechanical strain

Aquaporin-1 (AQP1) channels are expressed by trabecular meshwork (TM) and Schlemm's canal cells of the conventional outflow pathway where fluid movement is predominantly paracellular, suggesting a non-canonical role for AQP1. We hypothesized that AQP1 functions to protect TM cells during period...

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Veröffentlicht in:	Experimental eye research 2009-06, Vol.89 (1), p.95-100
Hauptverfasser:	Baetz, N.W., Hoffman, E.A., Yool, A.J., Stamer, W.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aquaporin 1 - metabolism Aquaporin 1 - physiology Cell Size Cell Survival - physiology cell viability cell volume Cells, Cultured glaucoma Homeostasis - physiology Humans Infant L-Lactate Dehydrogenase - metabolism Mechanotransduction, Cellular - physiology schlemm's canal Stress, Mechanical Trabecular Meshwork - cytology Trabecular Meshwork - metabolism Trabecular Meshwork - physiology
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