Does higher body mass index contribute to worse asthma control in an urban population?
Background Epidemiologic findings support a positive association between asthma and obesity. Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross-sectional assessment of asth...
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| creator | Clerisme-Beaty, Emmanuelle M., MD, MHS Karam, Sabine, MD Rand, Cynthia, PhD Patino, Cecilia M., MD Bilderback, Andrew, MS Riekert, Kristin A., PhD Okelo, Sande O., MD Diette, Gregory B., MD, MHS |
| description | Background Epidemiologic findings support a positive association between asthma and obesity. Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross-sectional assessment of asthma control was performed in patients with asthma recruited from primary care offices by using 4 different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ), and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control. Results Of 292 subjects with a mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% normal weight. The mean score from all 4 questionnaires showed an average suboptimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/ 25), ACQ (2.1/ 6), and ATAQ (1.3/ 4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all 4 questionnaires. This finding persisted even after adjusting for FEV1 , smoking status, race, sex, selected comorbid illnesses, and long-term asthma controller use. Conclusion Using 4 validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population. |
| doi_str_mv | 10.1016/j.jaci.2009.05.034 |
| format | Article |
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Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross-sectional assessment of asthma control was performed in patients with asthma recruited from primary care offices by using 4 different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ), and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control. Results Of 292 subjects with a mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% normal weight. The mean score from all 4 questionnaires showed an average suboptimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/ 25), ACQ (2.1/ 6), and ATAQ (1.3/ 4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all 4 questionnaires. This finding persisted even after adjusting for FEV1 , smoking status, race, sex, selected comorbid illnesses, and long-term asthma controller use. Conclusion Using 4 validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2009.05.034</identifier><identifier>PMID: 19615731</identifier><identifier>CODEN: JACIBY</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>ACCI ; African American ; Aged ; Allergies ; Allergy and Immunology ; Anti-Asthmatic Agents - therapeutic use ; Asthma ; Asthma - drug therapy ; Asthma - epidemiology ; Asthma - physiopathology ; asthma communication control instrument ; asthma control ; Biological and medical sciences ; Body mass ; Body Mass Index ; Chronic obstructive pulmonary disease, asthma ; Cross-Sectional Studies ; Female ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Humans ; Immune system ; Immunopathology ; inner city ; Linear Models ; Male ; Medical sciences ; Middle Aged ; Obesity ; Obesity - complications ; overweight ; Pneumology ; Prescription Drugs ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Spirometry ; Studies ; Surveys and Questionnaires ; United States - epidemiology ; Urban Population</subject><ispartof>Journal of allergy and clinical immunology, 2009-08, Vol.124 (2), p.207-212</ispartof><rights>American Academy of Allergy, Asthma & Immunology</rights><rights>2009 American Academy of Allergy, Asthma & Immunology</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Elsevier Limited Aug 2009</rights><rights>2009 American Academy of Allergy, Asthma and Immunology. Published by Mosby, Inc. All rights reserved. 2009</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c598t-d239e5d705d2adef3aa03ea5ee5b6167cd2bfff55aa233e958a38e1ea80a59413</citedby><cites>FETCH-LOGICAL-c598t-d239e5d705d2adef3aa03ea5ee5b6167cd2bfff55aa233e958a38e1ea80a59413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0091674909008586$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21820438$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19615731$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Clerisme-Beaty, Emmanuelle M., MD, MHS</creatorcontrib><creatorcontrib>Karam, Sabine, MD</creatorcontrib><creatorcontrib>Rand, Cynthia, PhD</creatorcontrib><creatorcontrib>Patino, Cecilia M., MD</creatorcontrib><creatorcontrib>Bilderback, Andrew, MS</creatorcontrib><creatorcontrib>Riekert, Kristin A., PhD</creatorcontrib><creatorcontrib>Okelo, Sande O., MD</creatorcontrib><creatorcontrib>Diette, Gregory B., MD, MHS</creatorcontrib><title>Does higher body mass index contribute to worse asthma control in an urban population?</title><title>Journal of allergy and clinical immunology</title><addtitle>J Allergy Clin Immunol</addtitle><description>Background Epidemiologic findings support a positive association between asthma and obesity. Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross-sectional assessment of asthma control was performed in patients with asthma recruited from primary care offices by using 4 different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ), and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control. Results Of 292 subjects with a mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% normal weight. The mean score from all 4 questionnaires showed an average suboptimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/ 25), ACQ (2.1/ 6), and ATAQ (1.3/ 4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all 4 questionnaires. This finding persisted even after adjusting for FEV1 , smoking status, race, sex, selected comorbid illnesses, and long-term asthma controller use. Conclusion Using 4 validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population.</description><subject>ACCI</subject><subject>African American</subject><subject>Aged</subject><subject>Allergies</subject><subject>Allergy and Immunology</subject><subject>Anti-Asthmatic Agents - therapeutic use</subject><subject>Asthma</subject><subject>Asthma - drug therapy</subject><subject>Asthma - epidemiology</subject><subject>Asthma - physiopathology</subject><subject>asthma communication control instrument</subject><subject>asthma control</subject><subject>Biological and medical sciences</subject><subject>Body mass</subject><subject>Body Mass Index</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Humans</subject><subject>Immune system</subject><subject>Immunopathology</subject><subject>inner city</subject><subject>Linear Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>overweight</subject><subject>Pneumology</subject><subject>Prescription Drugs</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Spirometry</subject><subject>Studies</subject><subject>Surveys and Questionnaires</subject><subject>United States - epidemiology</subject><subject>Urban Population</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk1v1DAQhiMEokvhD3BAkRDilDC248SRUBEqn1IlDnxcrYkz6Tok8WInhf33OOyqhR642LLmmZl3_E6SPGaQM2Dliz7v0dicA9Q5yBxEcSfZMKirrFRc3k02McCysirqk-RBCD3Et1D1_eSE1SWTlWCb5NsbRyHd2sst-bRx7T4dMYTUTi39So2bZm-bZaZ0dulP5wOlGObtiIeQGyKY4pQuvonnzu2WAWfrplcPk3sdDoEeHe_T5Ou7t1_OP2QXn95_PH99kRlZqzlruahJthXIlmNLnUAEQSiJZFOysjItb7qukxKRC0G1VCgUMUIFKOuCidPk7FB3tzQjtYaiKhz0ztsR_V47tPrfyGS3-tJdaV4JwQuIBZ4fC3j3Y6Ew69EGQ8OAE7klaFWVvOAgVCSf3iJ7t_gpTqeZhEIxWSgZKX6gjHcheOqutTDQq2u616trenVNg9TRtZj05O8pblKONkXg2RHAYHDoPE7GhmuOM8Wh-KPx5YGj-OdXlrwOxtJkqLWezKxbZ_-v4-xWuhnsZGPH77SncDOvDlyD_rzu17peUAMoqUrxG37By_M</recordid><startdate>20090801</startdate><enddate>20090801</enddate><creator>Clerisme-Beaty, Emmanuelle M., MD, MHS</creator><creator>Karam, Sabine, MD</creator><creator>Rand, Cynthia, PhD</creator><creator>Patino, Cecilia M., MD</creator><creator>Bilderback, Andrew, MS</creator><creator>Riekert, Kristin A., PhD</creator><creator>Okelo, Sande O., MD</creator><creator>Diette, Gregory B., MD, MHS</creator><general>Mosby, Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7TS</scope><scope>5PM</scope></search><sort><creationdate>20090801</creationdate><title>Does higher body mass index contribute to worse asthma control in an urban population?</title><author>Clerisme-Beaty, Emmanuelle M., MD, MHS ; Karam, Sabine, MD ; Rand, Cynthia, PhD ; Patino, Cecilia M., MD ; Bilderback, Andrew, MS ; Riekert, Kristin A., PhD ; Okelo, Sande O., MD ; Diette, Gregory B., MD, MHS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c598t-d239e5d705d2adef3aa03ea5ee5b6167cd2bfff55aa233e958a38e1ea80a59413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>ACCI</topic><topic>African American</topic><topic>Aged</topic><topic>Allergies</topic><topic>Allergy and Immunology</topic><topic>Anti-Asthmatic Agents - therapeutic use</topic><topic>Asthma</topic><topic>Asthma - drug therapy</topic><topic>Asthma - epidemiology</topic><topic>Asthma - physiopathology</topic><topic>asthma communication control instrument</topic><topic>asthma control</topic><topic>Biological and medical sciences</topic><topic>Body mass</topic><topic>Body Mass Index</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Humans</topic><topic>Immune system</topic><topic>Immunopathology</topic><topic>inner city</topic><topic>Linear Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>overweight</topic><topic>Pneumology</topic><topic>Prescription Drugs</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Spirometry</topic><topic>Studies</topic><topic>Surveys and Questionnaires</topic><topic>United States - epidemiology</topic><topic>Urban Population</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Clerisme-Beaty, Emmanuelle M., MD, MHS</creatorcontrib><creatorcontrib>Karam, Sabine, MD</creatorcontrib><creatorcontrib>Rand, Cynthia, PhD</creatorcontrib><creatorcontrib>Patino, Cecilia M., MD</creatorcontrib><creatorcontrib>Bilderback, Andrew, MS</creatorcontrib><creatorcontrib>Riekert, Kristin A., PhD</creatorcontrib><creatorcontrib>Okelo, Sande O., MD</creatorcontrib><creatorcontrib>Diette, Gregory B., MD, MHS</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Physical Education Index</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Clerisme-Beaty, Emmanuelle M., MD, MHS</au><au>Karam, Sabine, MD</au><au>Rand, Cynthia, PhD</au><au>Patino, Cecilia M., MD</au><au>Bilderback, Andrew, MS</au><au>Riekert, Kristin A., PhD</au><au>Okelo, Sande O., MD</au><au>Diette, Gregory B., MD, MHS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does higher body mass index contribute to worse asthma control in an urban population?</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>2009-08-01</date><risdate>2009</risdate><volume>124</volume><issue>2</issue><spage>207</spage><epage>212</epage><pages>207-212</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><coden>JACIBY</coden><abstract>Background Epidemiologic findings support a positive association between asthma and obesity. Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross-sectional assessment of asthma control was performed in patients with asthma recruited from primary care offices by using 4 different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ), and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control. Results Of 292 subjects with a mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% normal weight. The mean score from all 4 questionnaires showed an average suboptimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/ 25), ACQ (2.1/ 6), and ATAQ (1.3/ 4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all 4 questionnaires. This finding persisted even after adjusting for FEV1 , smoking status, race, sex, selected comorbid illnesses, and long-term asthma controller use. Conclusion Using 4 validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>19615731</pmid><doi>10.1016/j.jaci.2009.05.034</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | ACCI African American Aged Allergies Allergy and Immunology Anti-Asthmatic Agents - therapeutic use Asthma Asthma - drug therapy Asthma - epidemiology Asthma - physiopathology asthma communication control instrument asthma control Biological and medical sciences Body mass Body Mass Index Chronic obstructive pulmonary disease, asthma Cross-Sectional Studies Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immune system Immunopathology inner city Linear Models Male Medical sciences Middle Aged Obesity Obesity - complications overweight Pneumology Prescription Drugs Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Spirometry Studies Surveys and Questionnaires United States - epidemiology Urban Population |
| title | Does higher body mass index contribute to worse asthma control in an urban population? |
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