Plasma BDNF is reduced among middle-aged and elderly women with impaired insulin function: Evidence of a compensatory mechanism

Brain-derived neurotrophic factor (BDNF) plays a regulatory role in neuronal differentiation and synaptic plasticity and has been linked to glucose regulation and cognition. Associations among plasma BDNF, cognition, and insulin function were explored. Forty-one participants with impaired insulin fu...

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Veröffentlicht in:	Brain and cognition 2009-11, Vol.71 (2), p.147-152
Hauptverfasser:	Arentoft, Alyssa, Sweat, Victoria, Starr, Vanessa, Oliver, Stephen, Hassenstab, Jason, Bruehl, Hannah, Tirsi, Aziz, Javier, Elizabeth, McHugh, Pauline F., Convit, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Adults Age Factors Aged Analysis of Variance BDNF Biochemistry Biological and medical sciences Brain Brain-Derived Neurotrophic Factor - blood Brain-Derived Neurotrophic Factor - physiology Cognition Cognition - physiology Cognitive Processes Control Groups Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzyme-Linked Immunosorbent Assay Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Females Humans Insulin resistance Insulin Resistance - physiology Male Medical Evaluation Medical sciences Memory Memory - physiology Middle Aged Neurological Impairments Neuropsychological Tests Older Adults Organic mental disorders. Neuropsychology Patient Selection Prediction Psychological Evaluation Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Sex Characteristics Type 2 diabetes gender
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