A New Probabilistic Database Search Algorithm for ETD Spectra

Peptide characterization using electron transfer dissociation (ETD) is an important analytical tool for protein identification. The fragmentation observed in ETD spectra is complementary to that seen when using the traditional dissociation method, collision activated dissociation (CAD). Applications...

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Veröffentlicht in:	Journal of proteome research 2009-06, Vol.8 (6), p.3198-3205
Hauptverfasser:	Sadygov, Rovshan G, Good, David M, Swaney, Danielle L, Coon, Joshua J
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Databases, Protein Metalloendopeptidases - metabolism Myoglobin - chemistry Myoglobin - metabolism Peptide Fragments - chemistry Peptide Fragments - metabolism Proteomics - methods ROC Curve Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - metabolism Tandem Mass Spectrometry - methods Trypsin - metabolism
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