Engraftment of Syngeneic and Allogeneic Endothelial Cells, Hepatocytes and Cholangiocytes Into Partially Hepatectomized Rats Previously Treated With Mitomycin C

Pretreatment with retrorsine crosslinks host hepatocyte DNA and prevents proliferation after partial hepatectomy (PH), allowing selective expansion of transplanted progenitors. Shortcomings are length of protocol and carcinogenicity of retrorsine. This report describes a rapid liver repopulation pro...

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Veröffentlicht in:	Transplantation 2009-08, Vol.88 (4), p.486-495
Hauptverfasser:	BRILLIANT, Kate E, MILLS, David R, CALLANAN, Helen M, HIXSON, Douglas C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Bile Ducts - cytology Bile Ducts - enzymology Bile Ducts - transplantation Biological and medical sciences Cell Differentiation Cell Proliferation - drug effects Dipeptidyl Peptidase 4 - deficiency Dipeptidyl Peptidase 4 - genetics Dipeptidyl Peptidase 4 - metabolism Endothelial Cells - cytology Endothelial Cells - enzymology Endothelial Cells - transplantation Female Fundamental and applied biological sciences. Psychology Fundamental immunology Graft Enhancement, Immunologic Hepatectomy Hepatocytes - cytology Hepatocytes - drug effects Hepatocytes - enzymology Hepatocytes - transplantation Liver Regeneration Medical sciences Mitomycin - pharmacology Pregnancy Pyrrolizidine Alkaloids - pharmacology Rats Rats, Inbred ACI Rats, Inbred F344 Rats, Mutant Strains Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Transplantation, Homologous Transplantation, Isogeneic
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