Genetic Variation in the Chromosome 17q23 Amplicon and Breast Cancer Risk

Background: Gene amplification leading to overexpression is a common event in breast tumors that is linked to tumor development and progression. The 17q23 region is amplified in >40% of breast tumors and contains several candidate oncogenes. Because common genetic variation in several oncogenes h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2009-06, Vol.18 (6), p.1864-1868
Hauptverfasser:	KELEMEN, Linda E, XIANSHU WANG, GOODE, Ellen L, OLSON, Janet E, COUCH, Fergus J, FREDERICKSEN, Zachary S, PANKRATZ, V. Shane, PHAROAH, Paul D. P, AHMED, Shahana, DUNNING, Alison M, EASTON, Douglas F, VIERKANT, Robert A, CERHAN, James R
Format:	Artikel
Sprache:	eng
Schlagworte:	17q23 Adult Aged Association Biological and medical sciences Breast Neoplasms - genetics Chromosomes, Human, Pair 17 - genetics Female Gene Amplification Genetic Predisposition to Disease Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Middle Aged Polymorphism, Single Nucleotide Risk Factors Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!