Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic mice

We showed that Eμ-MiR-155 transgenic mice develop acute lymphoblastic leukemia/high-grade lymphoma. Most of these leukemias start at approximately 9 months irrespective of the mouse strain. They are preceded by a polyclonal pre–B-cell proliferation, have variable clinical presentation, are transplan...

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Veröffentlicht in:	Blood 2009-08, Vol.114 (7), p.1374-1382
Hauptverfasser:	Costinean, Stefan, Sandhu, Sukhinder K., Pedersen, Irene M., Tili, Esmerina, Trotta, Rossana, Perrotti, Danilo, Ciarlariello, David, Neviani, Paolo, Harb, Jason, Kauffman, Lauren Rachel, Shidham, Aaditya, Croce, Carlo Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Biological and medical sciences Experimental malignant blood diseases Hematologic and hematopoietic diseases Lymphoid Neoplasia Medical sciences Tumors
Online-Zugang:	Volltext
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