Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions

The architecture of the chromatin fiber, which determines DNA accessibility for transcription and other template-directed biological processes, remains unknown. Here we investigate the internal organization of the 30-nm chromatin fiber, combining Monte Carlo simulations of nucleosome chain folding w...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-08, Vol.106 (32), p.13317-13322
Hauptverfasser:	Grigoryev, Sergei A, Arya, Gaurav, Correll, Sarah, Woodcock, Christopher L, Schlick, Tamar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bending Biochemistry Biological Sciences Cations Chickens Chromatin Chromosomes Conformity Deoxyribonucleic acid Divalent cations DNA Genetic linkage Histones Histones - metabolism Membranes Modeling Models, Molecular Nucleic Acid Conformation Nucleosomes Nucleosomes - chemistry Nucleosomes - metabolism Nucleosomes - ultrastructure Proteins Solenoids
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