Comparative Methylation of ERVWE1/Syncytin-1 and Other Human Endogenous Retrovirus LTRs in Placenta Tissues

Human endogenous retroviruses (HERVs) are globally silent in somatic cells. However, some HERVs display high transcription in physiological conditions. In particular, ERVWE1, ERVFRDE1 and ERV3, three proviruses of distinct families, are highly transcribed in placenta and produce envelope proteins as...

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Veröffentlicht in:	DNA research 2009-08, Vol.16 (4), p.195-211
Hauptverfasser:	Gimenez, Juliette, Montgiraud, Cécile, Oriol, Guy, Pichon, Jean-Philippe, Ruel, Karine, Tsatsaris, Vassilis, Gerbaud, Pascale, Frendo, Jean-Louis, Evain-Brion, Danièle, Mallet, François
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Cell Line, Tumor Cells, Cultured CpG Islands DNA Methylation Endogenous Retroviruses - genetics Endogenous Retroviruses - metabolism Female Fibroblasts - cytology Fibroblasts - virology Fundamental and applied biological sciences. Psychology Gene Expression Regulation Gene Products, env - genetics Gene Products, env - metabolism Genes. Genome Genetics of eukaryotes. Biological and molecular evolution Humans Molecular and cellular biology Molecular genetics Molecular Sequence Data Placenta - cytology Placenta - metabolism Placenta - virology Pregnancy Proteins - genetics Pregnancy Proteins - metabolism Promoter Regions, Genetic Terminal Repeat Sequences - genetics
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