FGFR-1 is required by epicardium-derived cells for myocardial invasion and correct coronary vascular lineage differentiation

Critical steps in coronary vascular formation include the epithelial–mesenchyme transition (EMT) that epicardial cells undergo to become sub-epicardial; the invasion of the myocardium; and the differentiation of coronary lineages. However, the factors controlling these processes are not completely u...

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Veröffentlicht in:	Developmental biology 2009-04, Vol.328 (1), p.148-159
Hauptverfasser:	Pennisi, David J., Mikawa, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Avian embryo Cell Differentiation Cell Lineage Cell Movement Coronary vascular development Coronary Vessels - embryology Coronary Vessels - metabolism Coronary Vessels - physiology Embryo, Nonmammalian Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Epicardial EMT FGFR-1 Myocardial invasion Myocardium - cytology Myocardium - metabolism Myocytes, Smooth Muscle - metabolism Pericardium - cytology Pericardium - embryology Pericardium - metabolism Quail Receptor, Fibroblast Growth Factor, Type 1 - metabolism
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