Hin recombinase assembles a tetrameric protein swivel that exchanges DNA strands

Most site-specific recombinases can be grouped into two structurally and mechanistically different classes. Whereas recombination by tyrosine recombinases proceeds with little movements by the proteins, serine recombinases exchange DNA strands by a mechanism requiring large quaternary rearrangements...

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Veröffentlicht in:	Nucleic acids research 2009-08, Vol.37 (14), p.4743-4756
Hauptverfasser:	Dhar, Gautam, McLean, Meghan M, Heiss, John K, Johnson, Reid C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Cross-Linking Reagents Cysteine - chemistry DNA - chemistry DNA - metabolism DNA Nucleotidyltransferases - chemistry DNA Nucleotidyltransferases - genetics DNA Nucleotidyltransferases - metabolism Models, Molecular Molecular Sequence Data Mutation Nucleic Acid Enzymes Protein Multimerization Protein Subunits - chemistry Protein Subunits - metabolism Recombinases - chemistry Recombinases - genetics Recombinases - metabolism
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