The Impact of Nelfinavir Exposure on Cancer Development Among a Large Cohort of HIV-Infected Patients

BACKGROUND:Preclinical studies suggest that the antiretroviral agent, nelfinavir mesylate (NFV), may have antineoplastic properties. The relationship between NFV and cancer incidence among HIV-infected patients is unknown. METHODS:We evaluated the impact of NFV on cancer development in a large cohor...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2009-07, Vol.51 (3), p.305-309
Hauptverfasser:	Crum-Cianflone, Nancy F, Hullsiek, Katherine Huppler, Marconi, Vincent, Weintrob, Amy, Ganesan, Anuradha, Barthel, R Vincent, Fraser, Susan, Roediger, Mollie Poehlman, Agan, Brian, Wegner, Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticarcinogenic Agents - administration & dosage Antiretroviral drugs Antiretroviral Therapy, Highly Active Biological and medical sciences Cancer Cohort Studies Comparative analysis Female Fundamental and applied biological sciences. Psychology HIV HIV Infections - complications HIV Infections - drug therapy HIV Protease Inhibitors - administration & dosage Human immunodeficiency virus Human viral diseases Humans Infectious diseases Male Medical sciences Microbiology Miscellaneous Nelfinavir - administration & dosage Neoplasms - epidemiology Neoplasms - etiology Neoplasms - prevention & control Proportional Hazards Models Retrospective Studies Risk Risk factors Tumors Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology
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