Prediction of drug–target interaction networks from the integration of chemical and genomic spaces

Motivation: The identification of interactions between drugs and target proteins is a key area in genomic drug discovery. Therefore, there is a strong incentive to develop new methods capable of detecting these potential drug–target interactions efficiently. Results: In this article, we characterize...

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Veröffentlicht in:	Bioinformatics 2008-07, Vol.24 (13), p.i232-i240
Hauptverfasser:	Yamanishi, Yoshihiro, Araki, Michihiro, Gutteridge, Alex, Honda, Wataru, Kanehisa, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Chromosome Mapping - methods Computer Simulation Drug Delivery Systems - methods Models, Chemical Models, Genetic Pharmaceutical Preparations - chemistry Protein Binding Protein Interaction Mapping - methods Proteins - chemistry Proteins - genetics Systems Integration
Online-Zugang:	Volltext
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