A Unique Human Chorionic Gonadotropin Antagonist Suppresses Ovarian Hyperstimulation Syndrome in Rats

Ovarian hyperstimulation syndrome (OHSS) is a complication of in vitro fertilization associated with physiological changes after hCG administration to induce final oocyte maturation. It presents as widespread increases in vascular permeability and, in rare cases, results in cycle cancellation, multi...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2009-08, Vol.150 (8), p.3807-3814
Hauptverfasser:	Vardhana, Pratibhasri A, Julius, Martin A, Pollak, Susan V, Lustbader, Evan G, Trousdale, Rhonda K, Lustbader, Joyce W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Biological and medical sciences Blastocyst - drug effects Blotting, Western Chorionic gonadotropin Chorionic Gonadotropin - antagonists & inhibitors Chorionic Gonadotropin - chemistry Chorionic Gonadotropin - genetics Chorionic Gonadotropin - metabolism Female Fundamental and applied biological sciences. Psychology Gametocytes Glycosylation Gonadotropins Growth factors Hormone Antagonists - chemistry Hormone Antagonists - metabolism Hormone Antagonists - pharmacology Humans In vitro fertilization Luteinizing hormone Ovarian hyperstimulation syndrome Ovarian Hyperstimulation Syndrome - drug therapy Ovaries Ovulation Ovulation - drug effects Permeability Physiological effects Physiology Pituitary (anterior) Protein Binding Rats Receptors Receptors, LH - metabolism Reverse Transcriptase Polymerase Chain Reaction Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-2 - genetics Vascular Endothelial Growth Factor Receptor-2 - metabolism Vertebrates: endocrinology
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