Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

Cadherin-based adherens junctions (AJs) mediate cell adhesion and regulate cell shape change. The nectin-afadin complex also localizes to AJs and links to the cytoskeleton. Mammalian afadin has been suggested to be essential for adhesion and polarity establishment, but its mechanism of action is unc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of cell biology 2009-07, Vol.186 (1), p.57-73
Hauptverfasser:	Sawyer, Jessica K, Harris, Nathan J, Slep, Kevin C, Gaul, Ulrike, Peifer, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins Actins - metabolism Actomyosin - metabolism Adherens junctions Adherens Junctions - metabolism alpha Catenin - metabolism Animals Cadherins - metabolism Canoes Cell adhesion Cell adhesion & migration Cell Polarity Cell Surface Extensions - metabolism Cells Cytoskeleton Cytoskeleton - metabolism Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - embryology Drosophila melanogaster - metabolism Drosophila Proteins - deficiency Drosophila Proteins - metabolism Embryos Epithelial cells Gene expression regulation Genetic linkage Insects Mesoderm Mesoderm - metabolism Microfilament Proteins - chemistry Morphogenesis Mutation - genetics Organ Specificity Physiological regulation Protein Binding Protein Transport Proteins Rabbits rap1 GTP-Binding Proteins - metabolism Sequence Homology, Amino Acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!