Getting specialized: presynaptic and postsynaptic dopamine D2 receptors

Dopamine (DA) signaling controls many physiological functions ranging from locomotion to hormone secretion, and plays a critical role in addiction. DA elevation, for instance in response to drugs of abuse, simultaneously activates neurons expressing different DA receptors; how responses from diverse...

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Veröffentlicht in:	Current opinion in pharmacology 2009-02, Vol.9 (1), p.53-58
Hauptverfasser:	De Mei, Claudia, Ramos, Maria, Iitaka, Chisato, Borrelli, Emiliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cocaine - pharmacology Dopamine - physiology Dopamine D2 Receptor Antagonists Internal Medicine Medical Education Mice Mice, Knockout Motor Activity - drug effects Mutation Neurons - physiology Receptors, Dopamine D2 - agonists Receptors, Dopamine D2 - genetics Receptors, Dopamine D2 - physiology Receptors, Presynaptic - agonists Receptors, Presynaptic - antagonists & inhibitors Receptors, Presynaptic - physiology Reinforcement (Psychology) Reward Synapses - physiology Synaptic Transmission
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