Linkage-Specific Avidity Defines the Lysine 63-Linked Polyubiquitin-Binding Preference of Rap80

Linkage-specific polyubiquitin recognition is thought to make possible the diverse set of functional outcomes associated with ubiquitination. Thus far, mechanistic insight into this selectivity has been largely limited to single domains that preferentially bind to lysine 48-linked polyubiquitin (K48...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular cell 2009-03, Vol.33 (6), p.775-783
Hauptverfasser:	Sims, Joshua J., Cohen, Robert E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Carrier Proteins - genetics Carrier Proteins - metabolism DNA-Binding Proteins Histone Chaperones Humans Lysine - genetics Lysine - metabolism Molecular Sequence Data Nuclear Proteins - genetics Nuclear Proteins - metabolism Polyubiquitin - chemistry Polyubiquitin - metabolism Proteasome Endopeptidase Complex - metabolism Protein Binding PROTEINS Sequence Homology, Amino Acid SIGNALING Ubiquitination
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!