Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

Bone tissue arises from mesenchymal cells induced into the osteoblast lineage by essential transcription factors and signaling cascades. MicroRNAs regulate biological processes by binding to mRNA 3′-untranslated region (UTR) sequences to attenuate protein synthesis. Here we performed microRNA profil...

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Veröffentlicht in:	The Journal of biological chemistry 2009-06, Vol.284 (23), p.15676-15684
Hauptverfasser:	Li, Zhaoyong, Hassan, Mohammad Q., Jafferji, Mohammed, Aqeilan, Rami I., Garzon, Ramiro, Croce, Carlo M., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics 3T3 Cells Animals Blotting, Western Cell Differentiation DNA Primers Gene Expression Profiling Mice MicroRNAs - genetics Osteoblasts - cytology Plasmids Rats Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA-Mediated Regulation and Noncoding RNAs Transfection
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