Spontaneous release of acetylcholine from autonomic nerves in the bladder

Background and purpose: Bladder contractility is regulated by intrinsic myogenic mechanisms interacting with autonomic nerves. In this study, we have investigated the physiological role of spontaneous release of acetylcholine in guinea pig and rat bladders. Experimental approach: Conventional isot...

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Veröffentlicht in:	British journal of pharmacology 2009-06, Vol.157 (4), p.607-619
Hauptverfasser:	Zagorodnyuk, VP, Gregory, S, Costa, M, Brookes, SJH, Tramontana, M, Giuliani, S, Maggi, CA
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - metabolism Animals Autonomic Pathways - anatomy & histology Autonomic Pathways - metabolism Biological and medical sciences bladder Calcium Channel Blockers - pharmacology cholinergic autonomic nerves contractile activity Guinea Pigs In Vitro Techniques Male Medical sciences Muscle Contraction - drug effects Muscle Contraction - physiology Muscle, Smooth - drug effects Muscle, Smooth - innervation Muscle, Smooth - physiology neuronal Ca2+ channels Pharmacology. Drug treatments Physostigmine - pharmacology Rats Rats, Sprague-Dawley Research Papers Scopolamine Hydrobromide - pharmacology Tetrodotoxin - pharmacology Urinary Bladder - drug effects Urinary Bladder - innervation Urinary Bladder - physiology
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