PRKCA: A Positional Candidate Gene for Body Mass Index and Asthma

Asthma incidence and prevalence are higher in obese individuals. A potential mechanistic basis for this relationship is pleiotropy. We hypothesized that significant linkage and candidate-gene association would be found for body mass index (BMI) in a population ascertained on asthma affection status....

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Veröffentlicht in:	American journal of human genetics 2009-07, Vol.85 (1), p.87-96
Hauptverfasser:	Murphy, Amy, Tantisira, Kelan G., Soto-Quirós, Manuel E., Avila, Lydiana, Klanderman, Barbara J., Lake, Stephen, Weiss, Scott T., Celedón, Juan C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Asthma Asthma - genetics Biological and medical sciences Body Mass Index Child Chromosomes Chronic obstructive pulmonary disease, asthma Comparative analysis Costa Rica Family Female Fundamental and applied biological sciences. Psychology General aspects. Genetic counseling Genes Genetics of eukaryotes. Biological and molecular evolution Humans Longitudinal Studies Male Medical genetics Medical sciences Molecular and cellular biology Parents & parenting Pneumology Polymorphism, Single Nucleotide Protein Kinase C-alpha - genetics Sex Characteristics
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