Quantitative grey matter histological measures do not correlate with grey matter probability values from in vivo MRI in the temporal lobe

Voxel-based morphometry (VBM) is commonly used to study systematic differences in brain morphology from patients with various disorders, usually by comparisons with control subjects. It has often been suggested, however, that VBM is also sensitive to variations in composition in grey matter. The nat...

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Veröffentlicht in:	Journal of neuroscience methods 2009-06, Vol.181 (1), p.111-118
Hauptverfasser:	Eriksson, S.H., Free, S.L., Thom, M., Symms, M.R., Martinian, L., Duncan, J.S., Sisodiya, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain Mapping Electroencephalography Epilepsy Epilepsy, Temporal Lobe - pathology Epilepsy, Temporal Lobe - surgery Female FSL Glial Fibrillary Acidic Protein - metabolism Humans Image Processing, Computer-Assisted - methods Magnetic Resonance Imaging - methods Male Middle Aged MRI Neuroglia - metabolism Neuroglia - pathology Neuronal density Neurons - metabolism Neurons - pathology Phosphopyruvate Hydratase - metabolism Probability SPM Statistics as Topic Temporal Lobe - pathology Voxel-based morphometry Young Adult
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