Health risk and biological effects of cardiac ionising imaging: from epidemiology to genes
Cardiac diagnostic or therapeutic testing is an essential tool for diagnosis and treatment of cardiovascular disease, but it also involves considerable exposure to ionizing radiation. Every exposure produces a corresponding increase in cancer risk, and risks are highest for radiation exposure during...
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| Veröffentlicht in: | International journal of environmental research and public health 2009-06, Vol.6 (6), p.1882-1893 |
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| container_title | International journal of environmental research and public health |
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| creator | Foffa, Ilenia Cresci, Monica Andreassi, Maria Grazia |
| description | Cardiac diagnostic or therapeutic testing is an essential tool for diagnosis and treatment of cardiovascular disease, but it also involves considerable exposure to ionizing radiation. Every exposure produces a corresponding increase in cancer risk, and risks are highest for radiation exposure during infancy and adolescence. Recent studies on chromosomal biomarkers corroborate the current radioprotection assumption showing that even modest radiation load due to cardiac catheter-based fluoroscopic procedures can damage the DNA of the cell. In this article, we review the biological and clinical risks of cardiac imaging employing ionizing radiation. We also discuss the perspectives offered by the use of molecular biomarkers in order to better assess the long-term development of health effects. |
| doi_str_mv | 10.3390/ijerph6061882 |
| format | Article |
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We also discuss the perspectives offered by the use of molecular biomarkers in order to better assess the long-term development of health effects.</description><subject>Biomarkers</subject><subject>Cancer</subject><subject>DNA Damage</subject><subject>Epidemiologic Studies</subject><subject>Epidemiology</subject><subject>Genes</subject><subject>Heart - diagnostic imaging</subject><subject>Heart - radiation effects</subject><subject>Human exposure</subject><subject>Humans</subject><subject>Polymorphism, Genetic</subject><subject>Radiation</subject><subject>Radiation protection</subject><subject>Radiation, Ionizing</subject><subject>Radiography</subject><subject>Risk Factors</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><issn>1661-7827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqFkUlLBDEQhYMo7kevEjx4a83eaQ-CiBsIXvTiJWSy9GTs7oxJj-C_N-rgdvFUReWrx6s8APYwOqK0Qcdh5tJ8KpDAUpIVsImFQBUTCK_-6DfAVs4zhKhkolkHG7jhdWnFJni8drobpzCF_AT1YOEkxC62wegOOu-dGTOMHhqdbNAGhjiEHIYWhl63pZ5An2IP3TxY139svsIxwtYNLu-ANa-77HaXdRs8XF7cn19Xt3dXN-dnt5VhjI4VtsJraxtLjS2ePJaNkIZ7TykjXBtfY2JdmU6YNqapsaVMI-knlCPOGKLb4PRTd76Y9M4aN4xJd2qeisf0qqIO6vfLEKaqjS-K1IgTQovA4VIgxeeFy6PqQzau6_Tg4iIrUTOOZTH7H0iQlBRzWcCDP-AsLtJQfkERUtOaSyIKVH1CJsWck_NfljFS79mqX9kWfv_nnd_0Mkz6BpcVod8</recordid><startdate>20090601</startdate><enddate>20090601</enddate><creator>Foffa, Ilenia</creator><creator>Cresci, Monica</creator><creator>Andreassi, Maria Grazia</creator><general>MDPI AG</general><general>Molecular Diversity Preservation International (MDPI)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7U1</scope><scope>7U2</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090601</creationdate><title>Health risk and biological effects of cardiac ionising imaging: from epidemiology to genes</title><author>Foffa, Ilenia ; 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| subjects | Biomarkers Cancer DNA Damage Epidemiologic Studies Epidemiology Genes Heart - diagnostic imaging Heart - radiation effects Human exposure Humans Polymorphism, Genetic Radiation Radiation protection Radiation, Ionizing Radiography Risk Factors |
| title | Health risk and biological effects of cardiac ionising imaging: from epidemiology to genes |
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