Thrombospondin-1 expression correlates with angiogenesis in experimental cirrhosis

AIM：To investigate the significance of Thrombospondin-1 （TSP-1） expression and its relationship with angiogenesis during experimental fibrosis. METHODS：Cirrhosis was induced in male Wistar rats by intraperitoneal administration of diethyl nitrosamine （DEN）. The serial sections from liver tissues wer...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2008-04, Vol.14 (14), p.2213-2217
Hauptverfasser:	Elpek, Gulsum-Ozlem, Gokhan, Guzide-Ayse, Bozova, Sevgi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD34 - biosynthesis Diethylnitrosamine - metabolism Disease Models, Animal Fibrosis - metabolism Gene Expression Regulation Immunohistochemistry - methods Inflammation Liver - pathology Male Neovascularization, Pathologic Rapid Communication Rats Rats, Wistar Thrombospondin 1 - biosynthesis 免疫组织化学肝硬化肝纤维化血管发生
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