Integrin clipping: A novel adhesion switch?

During human prostate cancer progression, the majority of normally expressed integrins are suppressed with the exception of the α6, α3, and β1 integrins. We have shown that in prostate cancer, the α6 integrin is found paired with the β1 integrin and that a novel form of the α6 integrin that lacks a...

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Veröffentlicht in:	Journal of cellular biochemistry 2004-01, Vol.91 (1), p.26-35
Hauptverfasser:	Demetriou, Manolis C., Cress, Anne E.
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion cancer progression Cell Adhesion Humans integrin Integrin alpha3 - metabolism Integrin alpha6 - metabolism Integrin beta1 - metabolism Male Prostatic Neoplasms - metabolism protease Protein Isoforms - metabolism Urokinase-Type Plasminogen Activator - metabolism
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