Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross

Human erythrocytes infected with the malaria parasite Plasmodium falciparum have increased permeabilities to many solutes. The plasmodial surface anion channel (PSAC) may mediate these changes. Despite good understanding of the biochemical and biophysical properties, the genetic basis of PSAC activi...

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Veröffentlicht in:	Molecular microbiology 2009-04, Vol.72 (2), p.459-469
Hauptverfasser:	Alkhalil, Abdulnaser, Pillai, Ajay D, Bokhari, Abdullah A.B, Vaidya, Akhil B, Desai, Sanjay A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Biological and medical sciences Crosses, Genetic DNA Fingerprinting Erythrocytes Erythrocytes - parasitology Fundamental and applied biological sciences. Psychology Furosemide - pharmacology Genetics Humans Inheritance Patterns Ion Channels - genetics Ions Life cycle. Host-agent relationship. Pathogenesis Malaria, Falciparum - parasitology Microbiology Mutation Osmosis Parasitic protozoa Patch-Clamp Techniques Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - genetics Polymorphism Polymorphism, Genetic Primates Protozoa Protozoan Proteins - genetics Quantitative Trait Loci Sorbitol - metabolism
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