Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

To track drainage of lymph-borne small and large antigens (Ags) into the peripheral lymph nodes and subsequent encounter by B cells and follicular dendritic cells, we used the approach of multiphoton intravital microscopy. We find a system of conduits that extend into the follicles and mediate deliv...

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