In search of nonribosomal nucleolar protein function and regulation
The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this subnuclear compartment have no identifiable tie either to the ribosome biosynthetic pathway or to the other newly established activities occurring...
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| Veröffentlicht in: | The Journal of cell biology 2009-03, Vol.184 (6), p.771-776 |
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| container_end_page | 776 |
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| container_title | The Journal of cell biology |
| container_volume | 184 |
| creator | Pederson, Thoru Tsai, Robert Y.L |
| description | The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this subnuclear compartment have no identifiable tie either to the ribosome biosynthetic pathway or to the other newly established activities occurring within the nucleolus. The questions of how and why these proteins end up in this subnuclear compartment remain unanswered and are the focus of intense current interest. This review discusses our thoughts on the discovery of nonribosomal proteins in the nucleolus. |
| doi_str_mv | 10.1083/jcb.200812014 |
| format | Article |
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Tsai, Robert Y.L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-4a962db0788c0bf89f222ce0ed960c5bb0de56bc92f147ca5027cc4631749a6f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Animals</topic><topic>Biochemistry</topic><topic>Cell Cycle</topic><topic>Cell Cycle Proteins - metabolism</topic><topic>Cell nucleolus</topic><topic>Cell Nucleolus - enzymology</topic><topic>Cell Nucleolus - metabolism</topic><topic>Cells</topic><topic>Gene expression regulation</topic><topic>HeLa cells</topic><topic>Humans</topic><topic>Mini-Review</topic><topic>Mitosis</topic><topic>Nuclear proteins</topic><topic>Nuclear Proteins - metabolism</topic><topic>Phosphoric Monoester Hydrolases - metabolism</topic><topic>Protein Transport</topic><topic>Proteins</topic><topic>Reviews</topic><topic>Ribonucleic acid</topic><topic>Ribosomal Proteins - metabolism</topic><topic>Ribosomes</topic><topic>RNA</topic><topic>RNA Precursors - metabolism</topic><topic>RNA, Ribosomal - metabolism</topic><topic>Stem cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pederson, Thoru</creatorcontrib><creatorcontrib>Tsai, Robert Y.L</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pederson, Thoru</au><au>Tsai, Robert Y.L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In search of nonribosomal nucleolar protein function and regulation</atitle><jtitle>The Journal of cell biology</jtitle><addtitle>J Cell Biol</addtitle><date>2009-03-23</date><risdate>2009</risdate><volume>184</volume><issue>6</issue><spage>771</spage><epage>776</epage><pages>771-776</pages><issn>0021-9525</issn><eissn>1540-8140</eissn><coden>JCLBA3</coden><abstract>The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. 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| ispartof | The Journal of cell biology, 2009-03, Vol.184 (6), p.771-776 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Animals Biochemistry Cell Cycle Cell Cycle Proteins - metabolism Cell nucleolus Cell Nucleolus - enzymology Cell Nucleolus - metabolism Cells Gene expression regulation HeLa cells Humans Mini-Review Mitosis Nuclear proteins Nuclear Proteins - metabolism Phosphoric Monoester Hydrolases - metabolism Protein Transport Proteins Reviews Ribonucleic acid Ribosomal Proteins - metabolism Ribosomes RNA RNA Precursors - metabolism RNA, Ribosomal - metabolism Stem cells |
| title | In search of nonribosomal nucleolar protein function and regulation |
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