Decreased Immune Responses to Influenza Vaccination in Patients With Heart Failure

Abstract Background Heart failure (HF) patients are at risk for influenza despite widespread vaccination. Both humoral (antibody) and cytotoxic T-lymphocyte (CTL) responses are important for protection. We explored antibody- and CTL-mediated responses to the influenza vaccine in HF patients compared...

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Veröffentlicht in:	Journal of cardiac failure 2009-05, Vol.15 (4), p.368-373
Hauptverfasser:	Vardeny, Orly, PharmD, Sweitzer, Nancy K., MD, PhD, Detry, Michelle A., PhD, Moran, John M., BS, Johnson, Maryl R., MD, Hayney, Mary S., PharmD, MPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antibodies, Viral - biosynthesis Antibodies, Viral - physiology Antibody-Dependent Cell Cytotoxicity Cardiovascular Cells, Cultured Cytotoxic T-lymphocyte (CTL) immune responses Female heart failure Heart Failure - drug therapy Heart Failure - immunology Heart Failure - virology Humans humoral vaccine responses influenza vaccine Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza Vaccines - therapeutic use Influenza, Human - immunology Influenza, Human - prevention & control Male Middle Aged Prospective Studies T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - microbiology
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