Regulation of mRNA stability through a pentobarbital-responsive element

Pentobarbital, a general anesthetic and non-genotoxic carcinogen, can induce gene expression by activating transcription. In the Drosophila glutathione S-transferase D21 ( gstD21) gene, pentobarbital’s regulatory influence extends to the level of mRNA turnover. Transcribed from an intronless gene, g...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2007-03, Vol.459 (1), p.143-150
Hauptverfasser:	Akgül, Bünyamin, Tu, Chen-Pei D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Drosophila - enzymology Drosophila - genetics Gene Expression Regulation - drug effects Gene Expression Regulation - genetics Glutathione Transferase - genetics Heat shock miRNA mRNA decay Pentobarbital Pentobarbital - administration & dosage Polysome Response Elements - genetics RNA Stability - drug effects RNA Stability - physiology RNA, Messenger - genetics
Online-Zugang:	Volltext
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