Refined mapping of loss of heterozygosity on 1q31.1-32.1 in sporadic colorectal carcinoma

AIM： To explore precise deleted regions and screen the candidate tumor suppressor genes related to sporadic colorectal carcinoma. METHODS： Six markers on 1q31.1-32.1 were chosen. These polymorphic microsatellite markers in 83 colorectal cancer patients tumor and normal DNA were analyzed via PCR. PCR...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2008-03, Vol.14 (10), p.1582-1587
Hauptverfasser:	Zhou, Chong-Zhi, Qiu, Guo-Qiang, Fan, Jun-Wei, Wang, Xiao-Liang, Tang, Hua-Mei, Huang, Li, Sun, Yu-Hao, Peng, Zhi-Hai
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adult Aged Aged, 80 and over Chromosome Mapping - methods Chromosomes, Human, Pair 1 - genetics Colorectal Neoplasms - genetics Female Gene Frequency - genetics Genes, Tumor Suppressor Genetic Markers - genetics Humans Loss of Heterozygosity - genetics Male Microsatellite Repeats - genetics Middle Aged Rapid Communication 基因多态性异型接合性结肠癌肿瘤抑制基因
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