Methods to determine DNA structural alterations and genetic instability

Chromosomal DNA is a dynamic structure that can adopt a variety of non-canonical (i.e., non-B) conformations. In this regard, at least 10 different forms of non-B DNA conformations have been identified; many of them have been found to be mutagenic, and associated with human disease development. Desp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2009-05, Vol.48 (1), p.54-62
Hauptverfasser:	Wang, Guliang, Zhao, Junhua, Vasquez, Karen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Base Sequence Cell Line Chromosome Chromosome Aberrations Chromosomes, Artificial, Yeast DNA - chemistry DNA - genetics DNA Mutational Analysis DNA structure Genes, Reporter Genetic instability Genomic Instability Humans Mammal Methods Mice Mice, Transgenic Models, Genetic Molecular Sequence Data Nucleic Acid Conformation Plasmid Plasmids Repetitive Sequences, Nucleic Acid Reporter gene Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!