HIV Infection and the Central Nervous System: A Primer
The purpose of this brief review is to prepare readers who may be unfamiliar with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and the rapidly accumulating changes in the epidemic by providing an introduction to HIV disease and its treatment. The general concepts prese...
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| Veröffentlicht in: | Neuropsychology review 2009-06, Vol.19 (2), p.144-151 |
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| creator | Ellis, Ronald J. Calero, Patricia Stockin, Michael D. |
| description | The purpose of this brief review is to prepare readers who may be unfamiliar with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and the rapidly accumulating changes in the epidemic by providing an introduction to HIV disease and its treatment. The general concepts presented here will facilitate understanding of the papers in this issue on HIV-associated neurocognitive disorders (HAND). Toward that end, we briefly review the biology of HIV and how it causes disease in its human host, its epidemiology, and how antiretroviral treatments are targeted to interfere with the molecular biology that allows the virus to reproduce. Finally, we describe what is known about how HIV injures the nervous system, leading to HAND, and discuss potential strategies for preventing or treating the effects of HIV on the nervous system. |
| doi_str_mv | 10.1007/s11065-009-9094-1 |
| format | Article |
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classification</subject><subject>HIV Infections - classification</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - drug therapy</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Immune system</subject><subject>Infections</subject><subject>Lymphocytes</subject><subject>Nervous system</subject><subject>Neurology</subject><subject>Neuropsychology</subject><subject>Neurosciences</subject><subject>Review</subject><subject>Viral infections</subject><issn>1040-7308</issn><issn>1573-6660</issn><issn>1573-6660</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU1L5EAQhhtR_Fp_gBcJHrxFq7o7lbQHQQY_BmRXcHevTU9SGSMziXZnBP-9PWRw3AXxVA311Ftv9SvEIcIpAuRnAREoSwFMasDoFDfELma5SokINuMbNKS5gmJH7IXwBBCnpNwWO2g0ZhnArqDb8d9k3NZc9k3XJq6tkv6RkxG3vXez5Cf7124Rkoe30PP8PLlM7n0zZ_9DbNVuFvhgVffFn-ur36Pb9O7XzXh0eZeW2hR9WlcVaGUYjUPSjCQ1U1bXOqPonI1Ew6yhcJWTZTGhwuRIJlMTyHNUk1rti4tB93kxmXNVDrbsczTh_JvtXGP_7bTNo512r1aSgULJKHCyEvDdy4JDb-dNKHk2cy3HwyzlSgJm-C0ogUhrWioe_wc-dQvfxl-wUslC54WhCOEAlb4LwXP9YRnBLrOzQ3Y2ZmeX2dmlg6PPt64nVmFFQA5AiK12yn69-WvVd_3Jodg</recordid><startdate>20090601</startdate><enddate>20090601</enddate><creator>Ellis, Ronald J.</creator><creator>Calero, Patricia</creator><creator>Stockin, Michael D.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PADUT</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20090601</creationdate><title>HIV Infection and the Central Nervous System: A Primer</title><author>Ellis, Ronald J. ; Calero, Patricia ; Stockin, Michael D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-fdd0439e19a164e1624e65ff456106e9219ee408ada2c8b689716953b07713bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Acquired Immunodeficiency Syndrome - 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| subjects | Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - therapy AIDS Anti-Retroviral Agents - therapeutic use Antiretroviral drugs Antiretroviral Therapy, Highly Active - methods Biology Biomedical and Life Sciences Biomedicine Central Nervous System - virology Central Nervous System Diseases - etiology Central Nervous System Diseases - virology Cognition Disorders - etiology Cognition Disorders - virology Disease Drug resistance Drug therapy Enzymes Epidemiology HIV HIV - classification HIV Infections - classification HIV Infections - complications HIV Infections - drug therapy Human immunodeficiency virus Humans Immune system Infections Lymphocytes Nervous system Neurology Neuropsychology Neurosciences Review Viral infections |
| title | HIV Infection and the Central Nervous System: A Primer |
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