Microemulsion-Based Vaginal Gel of Clotrimazole: Formulation, In Vitro Evaluation, and Stability Studies

The objective of the present investigation was to develop and evaluate microemulsion-based gel for the vaginal delivery of clotrimazole (CMZ). The solubility of CMZ in oils and surfactants was evaluated to identify components of the microemulsion. The ternary diagram was plotted to identify the area...

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Veröffentlicht in:	AAPS PharmSciTech 2009-06, Vol.10 (2), p.476-481, Article 476
Hauptverfasser:	Bachhav, Yogeshwar G., Patravale, Vandana B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins Antifungal Agents - administration & dosage Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Chemistry, Pharmaceutical Clotrimazole - administration & dosage Clotrimazole - chemistry Clotrimazole - pharmacology Drug Stability Emulsions Microbial Sensitivity Tests Pharmacology/Toxicology Pharmacy Polyvinyls - administration & dosage Research Article Solubility Vaginal Creams, Foams, and Jellies
Online-Zugang:	Volltext
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