H pylori： Treatment for the patient only or the whole family
AIM： To compare the effects of treatment of H pyloriinfected individuals with the effects of treatment of individuals as well as all Hpylori-infected family members. METHODS： H pylori-positive patients with similar demographic specifications were prospectively randomized with respect to treatment, w...
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| Veröffentlicht in: | World journal of gastroenterology : WJG 2008-02, Vol.14 (8), p.1244-1247 |
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| container_title | World journal of gastroenterology : WJG |
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| creator | Sari, Yavuz-Selim Can, Didem Tunali, Vahit Sahin, Orhan Koc, Oguz Bender, Omer |
| description | AIM： To compare the effects of treatment of H pyloriinfected individuals with the effects of treatment of individuals as well as all Hpylori-infected family members.
METHODS： H pylori-positive patients with similar demographic specifications were prospectively randomized with respect to treatment, with a triple regimen of either patients and all Hpylori-positive family members living together （group Ⅰ ） or patients only （group Ⅱ）. Nine months after treatment, all patients were assessed for H pylori positivity.
RESULTS： There were 70 H pylori-positive patients in each group; patients in groups Ⅰ and Ⅱ lived with 175 and 190 Hpylori-positive relatives, respectively. Age, sex and Hpylori positivity rate were similar in both groups of relatives. Nine months after 14 d standard triple therapy, Hpylori positivity was 7.1% in group I patients and 38.6% in group 11 patients [P 〈 0.01, OR = 8.61 95% confidence interval （CI）： 2.91-22.84].
CONCLUSION： The present results indicate bad environmental hygienic conditions and close intra-familial relationships are important in H pylori contamination. These findings indicate all family members of H pyloripositive individuals should be assessed for H pylori positivity, particularly in developing countries where H pylori prevalence is high; they also suggest patients, their spouses and all H pyloN-positive family members of H pylori-positive individuals should be treated for H pylori infection. |
| doi_str_mv | 10.3748/wjg.14.1244 |
| format | Article |
| fullrecord | <record><control><sourceid>wanfang_jour_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2690673</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>26633120</cqvip_id><wanfj_id>wjg200808014</wanfj_id><sourcerecordid>wjg200808014</sourcerecordid><originalsourceid>FETCH-LOGICAL-c435t-b2d2ad4e76afd77ada2af9b738a0255dab8431750dd9c00b510b97185712ec5e3</originalsourceid><addsrcrecordid>eNpVkM9Kw0AQxhdRbK2evEsQb5I6-6-bXApS1AqCl3peJsmmTU2zdZNa8io-i-_kK7ihxT_MYZiZH998fIScUxhyJaKb7XI-pGJImRAHpM8YjUMWCTgkfQqgwpgz1SMndb0EYJxLdkx6NOIAXNI-GU-DdVtaV3x9fgQzZ7BZmaoJcuuCZmGCNTZFN9uqbIP9bruwpQlyXBVle0qOcixrc7bvA_JyfzebTMOn54fHye1TmAoumzBhGcNMGDXCPFMKM2SYx4niEQKTMsMkEpwqCVkWpwCJpJDEikZSUWZSafiAjHe6602yMlnqPTks9doVK3Sttljo_5eqWOi5fddsFMNIcS9wtRPYYpVjNddLu3GVt6x9fAwg8kWFx653WOpsXTuT_7ygoLu0O1xTobu0PX3x19Uvu4_XA5d7uYWt5m-F_5tg-poXpfHORpxTBvwbQ22HsA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>H pylori： Treatment for the patient only or the whole family</title><source>MEDLINE</source><source>Baishideng "World Journal of" online journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Sari, Yavuz-Selim ; Can, Didem ; Tunali, Vahit ; Sahin, Orhan ; Koc, Oguz ; Bender, Omer</creator><creatorcontrib>Sari, Yavuz-Selim ; Can, Didem ; Tunali, Vahit ; Sahin, Orhan ; Koc, Oguz ; Bender, Omer</creatorcontrib><description>AIM： To compare the effects of treatment of H pyloriinfected individuals with the effects of treatment of individuals as well as all Hpylori-infected family members.
METHODS： H pylori-positive patients with similar demographic specifications were prospectively randomized with respect to treatment, with a triple regimen of either patients and all Hpylori-positive family members living together （group Ⅰ ） or patients only （group Ⅱ）. Nine months after treatment, all patients were assessed for H pylori positivity.
RESULTS： There were 70 H pylori-positive patients in each group; patients in groups Ⅰ and Ⅱ lived with 175 and 190 Hpylori-positive relatives, respectively. Age, sex and Hpylori positivity rate were similar in both groups of relatives. Nine months after 14 d standard triple therapy, Hpylori positivity was 7.1% in group I patients and 38.6% in group 11 patients [P 〈 0.01, OR = 8.61 95% confidence interval （CI）： 2.91-22.84].
CONCLUSION： The present results indicate bad environmental hygienic conditions and close intra-familial relationships are important in H pylori contamination. These findings indicate all family members of H pyloripositive individuals should be assessed for H pylori positivity, particularly in developing countries where H pylori prevalence is high; they also suggest patients, their spouses and all H pyloN-positive family members of H pylori-positive individuals should be treated for H pylori infection.</description><identifier>ISSN: 1007-9327</identifier><identifier>EISSN: 2219-2840</identifier><identifier>DOI: 10.3748/wjg.14.1244</identifier><identifier>PMID: 18300351</identifier><language>eng</language><publisher>United States: SB Istanbul Training Hospital,Istanbul,Turkey%SB Okmeydani Training Hospital,Istanbul,Turkey</publisher><subject>Adenocarcinoma - prevention & control ; Adenocarcinoma - therapy ; Environment ; Family Health ; Female ; Gastroenterology - methods ; Helicobacter Infections - therapy ; Helicobacter Infections - transmission ; Helicobacter pylori - metabolism ; Humans ; Male ; Odds Ratio ; Peptic Ulcer - prevention & control ; Peptic Ulcer - therapy ; Prevalence ; Prospective Studies ; Rapid Communication ; Risk ; Stomach Neoplasms - prevention & control ; Stomach Neoplasms - therapy ; 幽门感染 ; 消化不良 ; 淋巴瘤 ; 胃腺癌</subject><ispartof>World journal of gastroenterology : WJG, 2008-02, Vol.14 (8), p.1244-1247</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2008 The WJG Press and Baishideng. All rights reserved. 2008</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c435t-b2d2ad4e76afd77ada2af9b738a0255dab8431750dd9c00b510b97185712ec5e3</citedby><cites>FETCH-LOGICAL-c435t-b2d2ad4e76afd77ada2af9b738a0255dab8431750dd9c00b510b97185712ec5e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84123X/84123X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690673/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690673/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18300351$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sari, Yavuz-Selim</creatorcontrib><creatorcontrib>Can, Didem</creatorcontrib><creatorcontrib>Tunali, Vahit</creatorcontrib><creatorcontrib>Sahin, Orhan</creatorcontrib><creatorcontrib>Koc, Oguz</creatorcontrib><creatorcontrib>Bender, Omer</creatorcontrib><title>H pylori： Treatment for the patient only or the whole family</title><title>World journal of gastroenterology : WJG</title><addtitle>World Journal of Gastroenterology</addtitle><description>AIM： To compare the effects of treatment of H pyloriinfected individuals with the effects of treatment of individuals as well as all Hpylori-infected family members.
METHODS： H pylori-positive patients with similar demographic specifications were prospectively randomized with respect to treatment, with a triple regimen of either patients and all Hpylori-positive family members living together （group Ⅰ ） or patients only （group Ⅱ）. Nine months after treatment, all patients were assessed for H pylori positivity.
RESULTS： There were 70 H pylori-positive patients in each group; patients in groups Ⅰ and Ⅱ lived with 175 and 190 Hpylori-positive relatives, respectively. Age, sex and Hpylori positivity rate were similar in both groups of relatives. Nine months after 14 d standard triple therapy, Hpylori positivity was 7.1% in group I patients and 38.6% in group 11 patients [P 〈 0.01, OR = 8.61 95% confidence interval （CI）： 2.91-22.84].
CONCLUSION： The present results indicate bad environmental hygienic conditions and close intra-familial relationships are important in H pylori contamination. These findings indicate all family members of H pyloripositive individuals should be assessed for H pylori positivity, particularly in developing countries where H pylori prevalence is high; they also suggest patients, their spouses and all H pyloN-positive family members of H pylori-positive individuals should be treated for H pylori infection.</description><subject>Adenocarcinoma - prevention & control</subject><subject>Adenocarcinoma - therapy</subject><subject>Environment</subject><subject>Family Health</subject><subject>Female</subject><subject>Gastroenterology - methods</subject><subject>Helicobacter Infections - therapy</subject><subject>Helicobacter Infections - transmission</subject><subject>Helicobacter pylori - metabolism</subject><subject>Humans</subject><subject>Male</subject><subject>Odds Ratio</subject><subject>Peptic Ulcer - prevention & control</subject><subject>Peptic Ulcer - therapy</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Rapid Communication</subject><subject>Risk</subject><subject>Stomach Neoplasms - prevention & control</subject><subject>Stomach Neoplasms - therapy</subject><subject>幽门感染</subject><subject>消化不良</subject><subject>淋巴瘤</subject><subject>胃腺癌</subject><issn>1007-9327</issn><issn>2219-2840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM9Kw0AQxhdRbK2evEsQb5I6-6-bXApS1AqCl3peJsmmTU2zdZNa8io-i-_kK7ihxT_MYZiZH998fIScUxhyJaKb7XI-pGJImRAHpM8YjUMWCTgkfQqgwpgz1SMndb0EYJxLdkx6NOIAXNI-GU-DdVtaV3x9fgQzZ7BZmaoJcuuCZmGCNTZFN9uqbIP9bruwpQlyXBVle0qOcixrc7bvA_JyfzebTMOn54fHye1TmAoumzBhGcNMGDXCPFMKM2SYx4niEQKTMsMkEpwqCVkWpwCJpJDEikZSUWZSafiAjHe6602yMlnqPTks9doVK3Sttljo_5eqWOi5fddsFMNIcS9wtRPYYpVjNddLu3GVt6x9fAwg8kWFx653WOpsXTuT_7ygoLu0O1xTobu0PX3x19Uvu4_XA5d7uYWt5m-F_5tg-poXpfHORpxTBvwbQ22HsA</recordid><startdate>20080228</startdate><enddate>20080228</enddate><creator>Sari, Yavuz-Selim</creator><creator>Can, Didem</creator><creator>Tunali, Vahit</creator><creator>Sahin, Orhan</creator><creator>Koc, Oguz</creator><creator>Bender, Omer</creator><general>SB Istanbul Training Hospital,Istanbul,Turkey%SB Okmeydani Training Hospital,Istanbul,Turkey</general><general>The WJG Press and Baishideng</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20080228</creationdate><title>H pylori： Treatment for the patient only or the whole family</title><author>Sari, Yavuz-Selim ; Can, Didem ; Tunali, Vahit ; Sahin, Orhan ; Koc, Oguz ; Bender, Omer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-b2d2ad4e76afd77ada2af9b738a0255dab8431750dd9c00b510b97185712ec5e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adenocarcinoma - prevention & control</topic><topic>Adenocarcinoma - therapy</topic><topic>Environment</topic><topic>Family Health</topic><topic>Female</topic><topic>Gastroenterology - methods</topic><topic>Helicobacter Infections - therapy</topic><topic>Helicobacter Infections - transmission</topic><topic>Helicobacter pylori - metabolism</topic><topic>Humans</topic><topic>Male</topic><topic>Odds Ratio</topic><topic>Peptic Ulcer - prevention & control</topic><topic>Peptic Ulcer - therapy</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Rapid Communication</topic><topic>Risk</topic><topic>Stomach Neoplasms - prevention & control</topic><topic>Stomach Neoplasms - therapy</topic><topic>幽门感染</topic><topic>消化不良</topic><topic>淋巴瘤</topic><topic>胃腺癌</topic><toplevel>online_resources</toplevel><creatorcontrib>Sari, Yavuz-Selim</creatorcontrib><creatorcontrib>Can, Didem</creatorcontrib><creatorcontrib>Tunali, Vahit</creatorcontrib><creatorcontrib>Sahin, Orhan</creatorcontrib><creatorcontrib>Koc, Oguz</creatorcontrib><creatorcontrib>Bender, Omer</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>World journal of gastroenterology : WJG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sari, Yavuz-Selim</au><au>Can, Didem</au><au>Tunali, Vahit</au><au>Sahin, Orhan</au><au>Koc, Oguz</au><au>Bender, Omer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>H pylori： Treatment for the patient only or the whole family</atitle><jtitle>World journal of gastroenterology : WJG</jtitle><addtitle>World Journal of Gastroenterology</addtitle><date>2008-02-28</date><risdate>2008</risdate><volume>14</volume><issue>8</issue><spage>1244</spage><epage>1247</epage><pages>1244-1247</pages><issn>1007-9327</issn><eissn>2219-2840</eissn><abstract>AIM： To compare the effects of treatment of H pyloriinfected individuals with the effects of treatment of individuals as well as all Hpylori-infected family members.
METHODS： H pylori-positive patients with similar demographic specifications were prospectively randomized with respect to treatment, with a triple regimen of either patients and all Hpylori-positive family members living together （group Ⅰ ） or patients only （group Ⅱ）. Nine months after treatment, all patients were assessed for H pylori positivity.
RESULTS： There were 70 H pylori-positive patients in each group; patients in groups Ⅰ and Ⅱ lived with 175 and 190 Hpylori-positive relatives, respectively. Age, sex and Hpylori positivity rate were similar in both groups of relatives. Nine months after 14 d standard triple therapy, Hpylori positivity was 7.1% in group I patients and 38.6% in group 11 patients [P 〈 0.01, OR = 8.61 95% confidence interval （CI）： 2.91-22.84].
CONCLUSION： The present results indicate bad environmental hygienic conditions and close intra-familial relationships are important in H pylori contamination. These findings indicate all family members of H pyloripositive individuals should be assessed for H pylori positivity, particularly in developing countries where H pylori prevalence is high; they also suggest patients, their spouses and all H pyloN-positive family members of H pylori-positive individuals should be treated for H pylori infection.</abstract><cop>United States</cop><pub>SB Istanbul Training Hospital,Istanbul,Turkey%SB Okmeydani Training Hospital,Istanbul,Turkey</pub><pmid>18300351</pmid><doi>10.3748/wjg.14.1244</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1007-9327 |
| ispartof | World journal of gastroenterology : WJG, 2008-02, Vol.14 (8), p.1244-1247 |
| issn | 1007-9327 2219-2840 |
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| source | MEDLINE; Baishideng "World Journal of" online journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adenocarcinoma - prevention & control Adenocarcinoma - therapy Environment Family Health Female Gastroenterology - methods Helicobacter Infections - therapy Helicobacter Infections - transmission Helicobacter pylori - metabolism Humans Male Odds Ratio Peptic Ulcer - prevention & control Peptic Ulcer - therapy Prevalence Prospective Studies Rapid Communication Risk Stomach Neoplasms - prevention & control Stomach Neoplasms - therapy 幽门感染 消化不良 淋巴瘤 胃腺癌 |
| title | H pylori： Treatment for the patient only or the whole family |
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