Functional recombinant MHC class II molecules and high-throughput peptide-binding assays

Molecules of the class II major histocompability complex (MHC-II) specifically bind and present exogenously derived peptide epitopes to CD4+ T helper cells. The extreme polymorphism of the MHC-II hampers the complete analysis of peptide binding. It is also a significant hurdle in the generation of M...

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Veröffentlicht in:	Immunome research 2009-05, Vol.5 (2), p.2-2
Hauptverfasser:	Justesen, Sune, Harndahl, Mikkel, Lamberth, Kasper, Nielsen, Lise-Lotte B, Buus, Søren
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological assay Genetic polymorphisms Major histocompatibility complex Physiological aspects
Online-Zugang:	Volltext
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